Tremor syndrome with central axonopathy
Central axonopathy · Congenital tremor with central axonopathy · Zentral-Axonopathie · Tremor-Syndrom mit zentraler Axonopathie · Axonopathy in Welsh Springer Spaniels
What it is
This is a severe, inherited neurological disorder affecting the brain and spinal cord, which make up the central nervous system. It is characterized by damage to axons, the long nerve fibers that transmit electrical signals between nerve cells. Because these fibers are damaged, the brain cannot communicate properly with the rest of the body.
How it presents
Owners will typically notice severe body tremors, coordination problems, and weakness in puppies starting around three to four weeks of age. These tremors usually become much more intense when the puppy tries to move purposefully, such as walking or reaching for food.
Treatment
There is no cure for this condition, and management is limited to supportive care. Because the disease progresses rapidly and severely impacts quality of life, early euthanasia is often necessary, with diagnostic and palliative costs typically ranging from 500 to 2,500 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.